The Pozo Santo Hospital is located in the square of the same name. It was founded in 1667 by the initiative of the nuns Marta de Jesús Carrillo and Beatriz Jerónima de la Concepción, from the Order of Franciscan Tertiaries. Both now rest in the right side wall of the church.
They named it after the Holy Christ Man of Sorrows, with the purpose of providing care to bedridden or blind women, a mission that continues today as a nursing home for the elderly.
Its common name is the Pozo Santo Hospital, due to its location in the square with that name, which originates from a curious legend: a child fell into a well at this site, and his mother prayed to the Virgin. The wells waters overflowed, and the child was saved. Today, all that remains of the well is the rim and an image of the Virgin at the moment of the miracle, which is venerated at the main altar of the nearby Mercy Hospital church.
The hospital has six rooms. A notable piece is a curious 16th-century painting about the plague epidemic in Seville, as well as a golden Baroque bed from the 18th century. On August 15, the image of the Virgin of the Transit is placed on this bed and carried in a procession through the convent. This is the only place where there are ten paintings of the Archangels, attributed to the workshop of Zurbarán.
Other artworks include portraits of the founding mothers, the Virgin by Francisco Meneses, the Divine Shepherdess by Cristóbal Ramos, the Virgin of Amparo, and the Assumption by Lucas Valdés.